Welcome to the Wiehe Group
Bioinformatics & Population Genetics
Research topics
Our main focus currently lies on investigating the evolutionary trajectory of multi-copy gene families.
We are using mathematical models to simulate recombination and compare the results with published data. Moreover, we apply bioinformatical methods to analyze our own sequencing data.
In particular, we are interested in copy number and sequence variation of the gene copies within and between wild and laboratory-held populations.
The gene families we are currently working on are olfactory receptors from beetles as well as nucleotide-binding, leucine-rich repeat containing genes (NLRs) from zebrafishes and plants.
Our goal is to elucidate the genetic and evolutionary mechanisms which confer the emergence and the development of such multi-copy gene families.